Organocatalytic enantio- and diastereoselective cycloetherification via dynamic kinetic resolution of chiral cyanohydrins
Enantioselective synthesis of six-membered oxacycles with multiple stereogenic centres is essential for the discovery of new therapeutic agents. Here the authors show organocatalytic cycloetherification for the highly enantio- and diastereoselective synthesis of tetrahydropyrans.
Váldodahkkit: | , , , , |
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Materiálatiipa: | Artihkal |
Giella: | English |
Almmustuhtton: |
Nature Portfolio
2017-11-01
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Ráidu: | Nature Communications |
Liŋkkat: | https://doi.org/10.1038/s41467-017-01099-x |