Dual separable feedback systems govern firing rate homeostasis
Firing rate homeostasis (FRH) stabilizes neural activity. A pervasive and intuitive theory argues that a single variable, calcium, is detected and stabilized through regulatory feedback. A prediction is that ion channel gene mutations with equivalent effects on neuronal excitability should invoke th...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-04-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/45717 |