Dual separable feedback systems govern firing rate homeostasis
Firing rate homeostasis (FRH) stabilizes neural activity. A pervasive and intuitive theory argues that a single variable, calcium, is detected and stabilized through regulatory feedback. A prediction is that ion channel gene mutations with equivalent effects on neuronal excitability should invoke th...
Main Authors: | Yelena Kulik, Ryan Jones, Armen J Moughamian, Jenna Whippen, Graeme W Davis |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/45717 |
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