A novel polyethylene glycol (PEG)‐drug conjugate of Venetoclax, a Bcl‐2 inhibitor, for treatment of acute myeloid leukemia (AML)

Abstract Background Venetoclax (VTX) is an anticancer drug. It is a selective Bcl‐2 inhibitor that is clinically used for the treatment of patients with lymphomas and leukemias. Treatment with VTX, however, is accompanied by severe adverse events such as tumor lysis syndrome and neutropenia, because...

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Bibliographic Details
Main Authors: Hidenori Ando, Yuta Murakami, Kiyoshi Eshima, Tatsuhiro Ishida
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.1485