Generation of Gene-Knockout Mongolian Gerbils via CRISPR/Cas9 System

Generation of Gene-Knockout Mongolian Gerbils via CRISPR/Cas9 System

The Mongolian gerbil (Meriones unguiculatus), a well-known “multifunctional” experimental animal, plays a crucial role in the research of hearing, cerebrovascular diseases and Helicobacter pylori infection. Although the whole-genome sequencing of Mongolian gerbils has been recently completed, lack o...

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Bibliographic Details
Main Authors: Yan Wang, Peikun Zhao, Zidai Song, Xiaoyan Du, Xueyun Huo, Jing Lu, Xin Liu, Jianyi Lv, Changlong Li, Meng Guo, Zhenwen Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Mongolian gerbils
CRISPR/Cas9
gene knockout
Cystatin C
Apolipoprotein A-II
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00780/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00780/full

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