Evolutionarily conserved Wnt/Sp5 signaling is critical for anterior-posterior axis patterning in sea urchin embryos

Summary: Studies across a diverse group of metazoan embryos indicate that Wnt signaling often activates the transcription factor Sp5, forming a signaling ‘cassette’ that plays critical roles in many developmental processes. This study explores the role of Wnt/Sp5 signaling during the specification a...

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Bibliographic Details
Main Authors: Sujan Gautam, Jennifer L. Fenner, Boyuan Wang, Ryan C. Range
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223026937