Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions

Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions

The paramyxoviral phosphoprotein (P protein) is the non-catalytic subunit of the viral RNA polymerase, and coordinates many of the molecular interactions required for RNA synthesis. All paramyxoviral P proteins oligomerize via a centrally located coiled-coil that is connected to a downstream binding...

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Bibliographic Details
Main Authors: Melissa N. Webby, Nicole Herr, Esther M. M. Bulloch, Michael Schmitz, Jeremy R. Keown, David C. Goldstone, Richard L. Kingston
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
Paramyxoviruses
RNA-dependent RNA polymerase
pararubulaviruses
intrinsically disordered proteins
protein self-association
conformational exchange
Online Access:https://www.mdpi.com/1999-4915/13/9/1737

Internet

https://www.mdpi.com/1999-4915/13/9/1737

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