Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells

Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells

BackgroundThe cyclic adenosine monophosphate/phosphodiesterase 4 (cAMP/PDE4) pathway is involved in inflammation and immune regulation; however, the effect of cAMP/PDE4 on immune infiltration and immune evasion in lung adenocarcinoma (LUAD) remains unclear.MethodsCBioPortal, which is the The Cancer...

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Bibliographic Details
Main Authors: Ling Tong, Minjie Shan, Wen Zou, XianLing Liu, Dean W. Felsher, Jingjing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
programmed cell death-ligand 1
cyclic adenosine monophosphate
immune infiltration
MYC
lung adenocarcinoma
the cancer genome atlas
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.904969/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.904969/full

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