Mitochondria in Huntington’s disease: implications in pathogenesis and mitochondrial-targeted therapeutic strategies

Mitochondria in Huntington’s disease: implications in pathogenesis and mitochondrial-targeted therapeutic strategies

Huntington’s disease is a genetic disease caused by expanded CAG repeats on exon 1 of the huntingtin gene located on chromosome 4. Compelling evidence implicates impaired mitochondrial energetics, altered mitochondrial biogenesis and quality control, disturbed mitochondrial trafficking, oxidative st...

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Detaylı Bibliyografya
Asıl Yazarlar: Anamaria Jurcau, Carolina Maria Jurcau
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Wolters Kluwer Medknow Publications 2023-01-01
Seri Bilgileri:Neural Regeneration Research
Konular:
antioxidants; calcium homeostasis; huntington’s disease; mitochondrial biogenesis; mitochondrial fission/fusion; mitochondrial trafficking; oxidative phosphorylation; oxidative stress; ss peptides; therapeutic intervention
Online Erişim:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1472;epage=1477;aulast=Jurcau

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1472;epage=1477;aulast=Jurcau

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