Macrophages and neutrophils express IFNλs in granulomas from Mycobacterium tuberculosis-infected nonhuman primates

Macrophages and neutrophils express IFNλs in granulomas from Mycobacterium tuberculosis-infected nonhuman primates

Granulomas are the hallmark of Mycobacterium tuberculosis (Mtb) infection. Cytokine-mediated signaling can modulate immune function; thus, understanding the cytokine milieu in granulomas is critical for understanding immunity in tuberculosis (TB). Interferons (IFNs) are important immune mediators in...

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Bibliographic Details
Main Authors: Priyanka Talukdar, Beth F. Junecko, Daniel S. Lane, Pauline Maiello, Joshua T. Mattila
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
granuloma
interferon lambda IFNλ
macrophage
neutrophil
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.985405/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.985405/full

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