Assessing Scientific Soundness and Translational Value of Animal Studies on DPP4 Inhibitors for Treating Type 2 Diabetes Mellitus

Assessing Scientific Soundness and Translational Value of Animal Studies on DPP4 Inhibitors for Treating Type 2 Diabetes Mellitus

Although there is a wide range of animal models of type 2 diabetes mellitus (T2DM) used in research; we have limited evidence on their translation value. This paper provides a) a comparison of preclinical animal and clinical results on the effect of five dipeptidyl peptidase-4 (DPP4) inhibitors by c...

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Bibliographic Details
Main Authors: Nuno Henrique Franco, Sonia Batista Miranda, Nóra Kovács, Attila Nagy, Bùi Quốc Thiện, Flávio Reis, Orsolya Varga
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biology
Subjects:
animal models
predictive validity
type 2 diabetes mellitus
translational medicine
research bias
Online Access:https://www.mdpi.com/2079-7737/10/2/155

Internet

https://www.mdpi.com/2079-7737/10/2/155

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