Glucocorticoid receptor-mediated cis-repression of osteogenic genes requires BRM-SWI/SNF

Glucocorticoids are an effective therapy for a variety of severe inflammatory and autoimmune disorders; however, the therapeutic use of glucocorticoids is severely limited by their negative side effects, particularly on osteogenesis. Glucocorticoids regulate transcription by binding to the glucocort...

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Bibliographic Details
Main Authors: Michael J. Pico, Sharareh Hashemi, Fuhua Xu, Kevin Hong Nguyen, Robert Donnelly, Elizabeth Moran, Stephen Flowers
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Bone Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187216300304