Glucocorticoid receptor-mediated cis-repression of osteogenic genes requires BRM-SWI/SNF
Glucocorticoids are an effective therapy for a variety of severe inflammatory and autoimmune disorders; however, the therapeutic use of glucocorticoids is severely limited by their negative side effects, particularly on osteogenesis. Glucocorticoids regulate transcription by binding to the glucocort...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
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Series: | Bone Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352187216300304 |