Synthesis of acetamidosulfonamide derivatives with antioxidative and QSAR studies

Synthesis of acetamidosulfonamide derivatives with antioxidative and QSAR studies

A series of sixteen acetamidosulfonamide derivatives (1-16) have been synthesized and investigated for their antioxidant (radical scavenging and superoxide dismutase (SOD)) and antimicrobial activities. Most compounds exhibited antioxidant activities in which compound 15 displayed the most potent ra...

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Bibliographic Details
Main Authors: Apilak Worachartcheewan, Somchai Pisutjaroenpong, Ratchanok Pingaew, Supaluk Prachayasittikul, Suphakit Siriwong, Somsak Ruchirawat, Virapong Prachayasittikul
Format: Article
Language:English
Published: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund 2022-02-01
Series:EXCLI Journal : Experimental and Clinical Sciences
Subjects:
sulfonamides
antioxidants
superoxide dismutase
qsar
rational design
Online Access:https://www.excli.de/index.php/excli/article/view/4590

Internet

https://www.excli.de/index.php/excli/article/view/4590

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