Lactobacillus brevis alleviates the progress of hepatocellular carcinoma and type 2 diabetes in mice model via interplay of gut microflora, bile acid and NOTCH 1 signaling

Lactobacillus brevis alleviates the progress of hepatocellular carcinoma and type 2 diabetes in mice model via interplay of gut microflora, bile acid and NOTCH 1 signaling

Type 2 diabetes (T2DM) clinically exhibits a higher incidence of hepatocellular carcinoma (HCC), contributing to a lousy prognosis in patients harboring both diseases. Microflora-based therapy draws attention with low side effects. Accumulating evidence shows that Lactobacillus brevis can improve bl...

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Bibliographic Details
Main Authors: Shujia Chen, Ping Han, Qian Zhang, Peiyan Liu, Jie Liu, Lili Zhao, Lianyi Guo, Jia Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
type 2 diabetes
hepatocellular carcinoma
Lactobacillus brevis
gut microflora
bile acids
NOTCH 1 signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179014/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179014/full

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