A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
Manganese (manganese ion; referred to as Mn) is essential for neuronal function, yet it is toxic at high concentrations. Environmental and occupational exposure to high concentrations of Mn causes manganism, a well-defined movement disorder in humans, with symptoms resembling Parkinson’s disease (PD...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-11-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/11/1239 |