VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO‐1 Signaling Pathway in Diabetic Nephropathy

VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO‐1 Signaling Pathway in Diabetic Nephropathy

Abstract Diabetic nephropathy (DN) is a serious microvascular complication of diabetes. Ferroptosis, a new form of cell death, plays a crucial role in the pathogenesis of DN. Renal tubular injury triggered by ferroptosis might be essential in this process. Numerous studies demonstrate that the vitam...

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Bibliographic Details
Main Authors: Hui Wang, Xiaoyue Yu, Dongwei Liu, Yingjin Qiao, Jinling Huo, Shaokang Pan, Lijuan Zhou, Rui Wang, Qi Feng, Zhangsuo Liu
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
diabetic nephropathy (DN)
ferroptosis
Nrf2/HO‐1 signaling pathway
renal tubular epithelial cell
vitamin D receptor (VDR)
Online Access:https://doi.org/10.1002/advs.202305563

Internet

https://doi.org/10.1002/advs.202305563

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