The reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword

The reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword

Abstract In Parkinson's disease (PD), neurotoxic microglia, Th1 cells, and Th17 cells are overactivated. Overactivation of these immune cells exacerbates the disease process and leads to the pathological development of pro-inflammatory cytokines, chemokines, and contact-killing compounds, causi...

Full description

Bibliographic Details
Main Authors: Yuxiang Xu, Yongjie Li, Changqing Wang, Tingting Han, Haixuan Liu, Lin Sun, Jun Hong, Makoto Hashimoto, Jianshe Wei
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
T cell
Cell–cell interactions
Chemokines
Parkinson’s disease
Cytokines
Online Access:https://doi.org/10.1186/s12974-023-02723-y

Internet

https://doi.org/10.1186/s12974-023-02723-y

Similar Items