The reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword
Abstract In Parkinson's disease (PD), neurotoxic microglia, Th1 cells, and Th17 cells are overactivated. Overactivation of these immune cells exacerbates the disease process and leads to the pathological development of pro-inflammatory cytokines, chemokines, and contact-killing compounds, causi...
Main Authors: | Yuxiang Xu, Yongjie Li, Changqing Wang, Tingting Han, Haixuan Liu, Lin Sun, Jun Hong, Makoto Hashimoto, Jianshe Wei |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-023-02723-y |
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