Breed‐Driven Microbiome Heterogeneity Regulates Intestinal Stem Cell Proliferation via Lactobacillus‐Lactate‐GPR81 Signaling

Breed‐Driven Microbiome Heterogeneity Regulates Intestinal Stem Cell Proliferation via Lactobacillus‐Lactate‐GPR81 Signaling

Abstract Genetically lean and obese individuals have distinct intestinal microbiota and function. However, the underlying mechanisms of the microbiome heterogeneity and its regulation on epithelial function such as intestinal stem cell (ISC) fate remain unclear. Employing pigs of genetically distinc...

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Bibliographic Details
Main Authors: Haiqin Wu, Chunlong Mu, Xuan Li, Wenlu Fan, Le Shen, Weiyun Zhu
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
intestinal stem cell
lactobacillus
microbiome
small intestine
wnt/β‐catenin signaling
Online Access:https://doi.org/10.1002/advs.202400058

Internet

https://doi.org/10.1002/advs.202400058

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