Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis

Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis

Chronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines...

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Bibliographic Details
Main Authors: Shaghayegh Pezeshki, Mir Hadi Jazayeri, Bahram Chahardouli, Nader Tajik, Seyyed Massood Nabavi, Mahdi Akbarzadeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
CD5 CD19 B cells
Chronic lymphocytic leukemia
Multiple sclerosis
Natural IgM
VH4-34 gene
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3620

Internet

https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3620

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