Excessive aggregation of fine particles may play a crucial role in adolescent spontaneous pneumothorax pathogenesis

Excessive aggregation of fine particles may play a crucial role in adolescent spontaneous pneumothorax pathogenesis

Background The pathogenesis of primary spontaneous pneumothorax (PSP) is unclear. Fine particles aggregated in the lung can be phagocytosed by alveolar macrophages (AMs) to induce an inflammatory reaction and damage local pulmonary tissue, which could be a mechanism of PSP. This project aimed to exp...

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Bibliographic Details
Main Authors: Sibo Wang, Jun Li, Mengjiao Qian, Jing Wang, Yongxing Tan, Haibo Ou, Zhongyin Wang, Xiao Chen, Yunjiao Tu, Kai Xu
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
Primary spontaneous pneumothorax
Fine particulate matter
Alveolar macrophage
Pulmonary elastic fiber
Matrix metalloproteinase-9
Monocyte chemoattractant protein-1
Online Access:https://peerj.com/articles/16484.pdf

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https://peerj.com/articles/16484.pdf

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