Prevention of Melanoma Extravasation as a New Treatment Option Exemplified by p38/MK2 Inhibition
Melanoma releases numerous tumor cells into the circulation; however, only a very small fraction of these cells is able to establish distant metastasis. Intravascular survival of circulating tumor cells is limited through hemodynamic forces and by the lack of matrix interactions. The extravasation s...
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Format: | Article |
Language: | English |
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MDPI AG
2020-11-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/21/21/8344 |