NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis

Introduction: Nuclear respiratory factor 1 (NRF1) is an important regulator involved in mitochondrial biogenesis and energy metabolism. However, the specific mechanism of NRF1 in anoikis and epithelial-mesenchymal transition (EMT) remains unclear. Methods: We examined the effect of NRF1 on mitochond...

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Bibliographic Details
Main Authors: Linjuan Sun BS, Nan Ouyang BS, Shaheryar Shafi MS, Rongchuan Zhao BS, Jinlin Pan BS, Lei Hong MS, Xueyan Song MS, Xiaohan Sa BS, Yuanshuai Zhou PhD
Format: Article
Language:English
Published: SAGE Publishing 2023-03-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338231161141