The Polymorphisms in <i>GSTO</i> Genes (<i>GSTO1</i> rs4925, <i>GSTO2</i> rs156697, and <i>GSTO2</i> rs2297235) Affect the Risk for Testicular Germ Cell Tumor Development: A Pilot Study

The Polymorphisms in <i>GSTO</i> Genes (<i>GSTO1</i> rs4925, <i>GSTO2</i> rs156697, and <i>GSTO2</i> rs2297235) Affect the Risk for Testicular Germ Cell Tumor Development: A Pilot Study

Members of the omega class of glutathione transferases (GSTs), GSTO1, and GSTO2, catalyze a range of reduction reactions as a part of the antioxidant defense system. Polymorphisms of genes encoding antioxidant proteins and the resultant altered redox profile have already been associated with the inc...

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Bibliographic Details
Main Authors: Milos Petrovic, Tatjana Simic, Tatjana Djukic, Tanja Radic, Ana Savic-Radojevic, Milica Zekovic, Otas Durutovic, Aleksandar Janicic, Bogomir Milojevic, Boris Kajmakovic, Marko Zivkovic, Nebojsa Bojanic, Uros Bumbasirevic, Vesna Coric
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Life
Subjects:
testicular GCT
glutathione transferase
<i>GSTO</i>
gene polymorphism
oxidative stress
Online Access:https://www.mdpi.com/2075-1729/13/6/1269

Internet

https://www.mdpi.com/2075-1729/13/6/1269

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