Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs

Abstract Background Pyroptosis of endothelial cells is a new cause of endothelial dysfunction in multiple diseases. Ceramide acts as a potential bioactive mediator of inflammation and increases vascular endothelial permeability in many diseases, whether it can aggravate vascular endothelial injury b...

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Bibliographic Details
Main Authors: Fangfang Liu, Yangyang Zhang, Yining Shi, Kai Xiong, Fugui Wang, Jin Yang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Molecular and Cell Biology
Subjects:
Ceramide
Endothelial cell
Cell pyroptosis
TXNIP/NLRP3/GSDMD signalling pathway
Vascular endothelial cell
Online Access:https://doi.org/10.1186/s12860-022-00459-w

Internet

https://doi.org/10.1186/s12860-022-00459-w

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