Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

The body plan along the anteroposterior axis and regional identities are specified by the spatiotemporal expression of Hox genes. Multistep controls are required for their unique expression patterns; however, the molecular mechanisms behind the tight control of Hox genes are not fully understood. In...

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Bibliographic Details
Main Authors: Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
Let-7
Hox
Polycomb
Lin28a
axial patterning
Online Access:https://elifesciences.org/articles/53608

Internet

https://elifesciences.org/articles/53608

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