Regulation of peripheral tissue substrate metabolism by the gut-derived hormone ghrelin

Ghrelin increases in the circulation prior to entrained mealtimes, with the acylated (AG) form functioning to stimulate food intake and growth hormone release. Acutely, AG induces whole-body insulin resistance, potentially to maintain glycemia between meals. Alternatively, chronic administration of...

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Bibliographic Details
Main Authors: Nicole M. Notaro, David J. Dyck
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Metabolism Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936824000112