Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards.

Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards.

Oseltamivir (Tamiflu®) is the most widely used drug against influenza infections and is extensively stockpiled worldwide as part of pandemic preparedness plans. However, resistance is a growing problem and in 2008-2009, seasonal human influenza A/H1N1 virus strains in most parts of the world carried...

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Bibliographic Details
Main Authors: Josef D Järhult, Shaman Muradrasoli, John Wahlgren, Hanna Söderström, Goran Orozovic, Gunnar Gunnarsson, Caroline Bröjer, Neus Latorre-Margalef, Jerker Fick, Roman Grabic, Johan Lennerstrand, Jonas Waldenström, Ake Lundkvist, Björn Olsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21931841/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21931841/pdf/?tool=EBI

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