B-cell lymphopoiesis is regulated by cathepsin L.

B-cell lymphopoiesis is regulated by cathepsin L.

Cathepsin L (CTSL) is a ubiquitously expressed lysosomal cysteine peptidase with diverse and highly specific functions. The involvement of CTSL in thymic CD4+ T-cell positive selection has been well documented. Using CTSL(nkt/nkt) mice that lack CTSL activity, we have previously demonstrated that th...

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Bibliographic Details
Main Authors: Maria Noel Badano, Gabriela Lorena Camicia, Gabriela Lombardi, Andrea Maglioco, Gabriel Cabrera, Hector Costa, Roberto Pablo Meiss, Isabel Piazzon, Irene Nepomnaschy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3621861?pdf=render

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http://europepmc.org/articles/PMC3621861?pdf=render

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