Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model.

Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model.

Emerging evidence suggests anti-cancer immunity is involved in the therapeutic effect induced by oncolytic viruses. Here we investigate the effect of Delta-24-RGD oncolytic adenovirus on innate and adaptive anti-glioma immunity.Mouse GL261-glioma model was set up in immunocompetent C57BL/6 mouse for...

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Bibliographic Details
Main Authors: Hong Jiang, Karen Clise-Dwyer, Kathryn E Ruisaard, Xuejun Fan, Weihua Tian, Joy Gumin, Martine L Lamfers, Anne Kleijn, Frederick F Lang, Wai-Kwan Alfred Yung, Luis M Vence, Candelaria Gomez-Manzano, Juan Fueyo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020829?pdf=render

Internet

http://europepmc.org/articles/PMC4020829?pdf=render

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