Optimization of l-malic acid production from acetate with Aspergillus oryzae DSM 1863 using a pH-coupled feeding strategy

Abstract Background Malic acid, a dicarboxylic acid mainly used in the food industry, is currently produced from fossil resources. The utilization of low-cost substrates derived from biomass could render microbial processes economic. Such feedstocks, like lignocellulosic hydrolysates or condensates...

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Bibliographic Details
Main Authors: Aline Kövilein, Vera Aschmann, Lena Zadravec, Katrin Ochsenreither
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-022-01961-8