In silico and in vitro evaluation of the anti-virulence potential of patuletin, a natural methoxy flavone, against Pseudomonas aeruginosa

This study aimed to investigate the potential of patuletin, a rare natural flavonoid, as a virulence and LasR inhibitor against Pseudomonas aeruginosa. Various computational studies were utilized to explore the binding of Patuletin and LasR at a molecular level. Molecular docking revealed that Patul...

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Bibliographic Details
Main Authors: Ahmed Metwaly, Moustafa M. Saleh, Aisha Alsfouk, Ibrahim M. Ibrahim, Muhamad Abd-Elraouf, Eslam Elkaeed, Hazem Elkady, Ibrahim Eissa
Format: Article
Language:English
Published: PeerJ Inc. 2024-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16826.pdf