An In Silico Design of Peptides Targeting the S1/S2 Cleavage Site of the SARS-CoV-2 Spike Protein

SARS-CoV-2, responsible for the COVID-19 pandemic, invades host cells via its spike protein, which includes critical binding regions, such as the receptor-binding domain (RBD), the S1/S2 cleavage site, the S2 cleavage site, and heptad-repeat (HR) sections. Peptides targeting the RBD and HR1 inhibit...

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Bibliographic Details
Main Authors: Chian Ho, Wan Fahmi Wan Mohamad Nazarie, Ping-Chin Lee
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/9/1930