Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

<p>Abstract</p> <p>Background</p> <p>Recent fate-mapping studies establish that microglia, the resident mononuclear phagocytes of the CNS, are distinct in origin from the bone marrow-derived myeloid lineage. Interferon regulatory factor 8 (IRF8, also known as interferon...

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Bibliographic Details
Main Authors: Horiuchi Makoto, Wakayama Kouji, Itoh Aki, Kawai Kumi, Pleasure David, Ozato Keiko, Itoh Takayuki
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Interferon regulatory factor
Phagocytosis
Cytokine
Cuprizone-induced demyelination
Online Access:http://www.jneuroinflammation.com/content/9/1/227

Internet

http://www.jneuroinflammation.com/content/9/1/227

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