Clostridioides difficile Infection Dysregulates Brain Dopamine Metabolism

Clostridioides difficile Infection Dysregulates Brain Dopamine Metabolism

ABSTRACT Gastrointestinal illnesses and dysbiosis are among the most common comorbidities reported in patients with neurodevelopmental disorders. The manuscript reports that C. difficile infection (CDI), predisposed by antibiotic-induced gut dysbiosis, causes significant alterations in dopamine meta...

Full description

Bibliographic Details
Main Authors: Akhil A. Vinithakumari, Piyush Padhi, Belen Hernandez, Susanne Je-Han Lin, Aaron Dunkerson-Kurzhumov, Lucas Showman, Matthew Breitzman, Caroline Stokes, Yousuf Sulaiman, Chandra Tangudu, Deepa A. Kuttappan, Muhammed S. Muyyarikkandy, Auriel A. Willette, Gregory J. Phillips, Vellareddy Anantharam, Ann Perera, Brett A. Sponseller, Anumantha Kanthasamy, Shankumar Mooyottu
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
gut-brain axis
Clostridioides difficile
p-cresol
dopamine
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00073-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00073-22

Similar Items