HCV Activates Somatic L1 Retrotransposition—A Potential Hepatocarcinogenesis Pathway

HCV Activates Somatic L1 Retrotransposition—A Potential Hepatocarcinogenesis Pathway

Hepatitis C virus (HCV) is a common cause of hepatocellular carcinoma (HCC). The activation and mutagenic consequences of L1 retrotransposons in virus-associated-HCC have been documented. However, the direct influence of HCV upon L1 elements is unclear, and is the focus of the present study. L1 tran...

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Bibliographic Details
Main Authors: Praveen D. Sudhindar, Daniel Wainwright, Santu Saha, Rachel Howarth, Misti McCain, Yvonne Bury, Sweta S. Saha, Stuart McPherson, Helen Reeves, Arvind H. Patel, Geoffrey J. Faulkner, John Lunec, Ruchi Shukla
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
L1
HCV
retrotransposition
DNA damage
hepatocellular carcinoma
Online Access:https://www.mdpi.com/2072-6694/13/20/5079

Internet

https://www.mdpi.com/2072-6694/13/20/5079

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