Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector

Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector

Exclusion of the transcription factor Max from the nucleus of retinal ganglion cells is an early, caspase-independent event of programmed cell death following damage to the optic axons. To test whether the loss of nuclear Max leads to a reduction in neuroprotection, we developed a procedure to overe...

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Bibliographic Details
Main Authors: H. Petrs-Silva, V. Chiodo, L.B. Chiarini, W.W. Hauswirth, R. Linden
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Retina
Max expression
Transcription factor
Viral vector
Gene therapy
Neuroprotection
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300008

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