Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages

Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages

Abstract Background Stimulator of IFN genes (STING) is highly expressed in the livers of non-alcoholic fatty liver disease (NAFLD) patients and high fat diet (HFD) induced NAFLD mice model. The STING signaling-mediated inflammation has been shown to play a critical role in metabolic disorders. Lingg...

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Bibliographic Details
Main Authors: Lin Cao, Erjin Xu, Rendong Zheng, Zhili Zhangchen, Rongling Zhong, Fei Huang, Juan Ye, Hongping Sun, Yaofu Fan, Shaofeng Xie, Yu Chen, Yijiao Xu, Jing Cao, Wen Cao, Chao Liu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Chinese Medicine
Subjects:
Lingguizhugan decoction (LGZG)
Hepatic steatosis
STING
Inflammation
Online Access:https://doi.org/10.1186/s13020-021-00559-3

Internet

https://doi.org/10.1186/s13020-021-00559-3

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