Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ

Frequent discrepancies between preclinical and clinical results of anticancer agents demand a reliable translational platform that can precisely recapitulate the biology of human cancers. Another critical unmet need is the ability to predict therapeutic responses for individual patients. Toward this...

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Bibliographic Details
Main Authors: Kyeung Min Joo, Jinkuk Kim, Juyoun Jin, Misuk Kim, Ho Jun Seol, Johongir Muradov, Heekyoung Yang, Yoon-La Choi, Woong-Yang Park, Doo-Sik Kong, Jung-Il Lee, Young-Hyeh Ko, Hyun Goo Woo, Jeongwu Lee, Sunghoon Kim, Do-Hyun Nam
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004585