Simultaneous Determination of Escitalopram Impurities including the <i>R</i>-enantiomer on a Cellulose tris(3,5-Dimethylphenylcarbamate)-Based Chiral Column in Reversed-Phase Mode

Simultaneous Determination of Escitalopram Impurities including the <i>R</i>-enantiomer on a Cellulose tris(3,5-Dimethylphenylcarbamate)-Based Chiral Column in Reversed-Phase Mode

A high-performance liquid chromatographic method was developed for the simultaneous determination of the related substances—three potential synthesis-related chemical impurities and the distomer—of escitalopram. The separation capacity of seven different polysaccharide-type chiral columns, including...

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Bibliographic Details
Main Authors: Zoltán-István Szabó, Ágnes Bartalis-Fábián, Gergő Tóth
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
citalopram
Lux Cellulose-1
reversed-phase enantioseparation
chemoselectivity
chiral separation
Online Access:https://www.mdpi.com/1420-3049/27/24/9022

Internet

https://www.mdpi.com/1420-3049/27/24/9022

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