Systematic Analysis of Covalent and Allosteric Protein Kinase Inhibitors

In drug discovery, protein kinase inhibitors (PKIs) are intensely investigated as drug candidates in different therapeutic areas. While ATP site-directed, non-covalent PKIs have long been a focal point in protein kinase (PK) drug discovery, in recent years, there has been increasing interest in allo...

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Bibliographic Details
Main Authors: Elena Xerxa, Oliver Laufkötter, Jürgen Bajorath
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/15/5805