Cooperation of Oligodeoxynucleotides and Synthetic Molecules as Enhanced Immune Modulators

Unmethylated cytosine–guanine dinucleotide (CpG) motifs are potent stimulators of the host immune response. Cellular recognition of CpG motifs occurs via Toll-like receptor 9 (TLR9), which normally activates immune responses to pathogen-associated molecular patterns (PAMPs) indicative of infection....

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Bibliographic Details
Main Authors: Shireen Nigar, Takeshi Shimosato
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnut.2019.00140/full