Inference of Selection from Genetic Time Series Using Various Parametric Approximations to the Wright-Fisher Model

Inference of Selection from Genetic Time Series Using Various Parametric Approximations to the Wright-Fisher Model

Detecting genomic regions under selection is an important objective of population genetics. Typical analyses for this goal are based on exploiting genetic diversity patterns in present time data but rapid advances in DNA sequencing have increased the availability of time series genomic data. A commo...

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Bibliographic Details
Main Authors: Cyriel Paris, Bertrand Servin, Simon Boitard
Format: Article
Language:English
Published: Oxford University Press 2019-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
genetic time series
hidden markov models
method of moments
selection
wright-fisher
beta with spikes
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400778

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http://g3journal.org/lookup/doi/10.1534/g3.119.400778

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