Morphine Postconditioning Protects Against Reperfusion Injury: the Role of Protein Kinase C-Epsilon, Extracellular Signal-Regulated Kinase 1/2 and Mitochondrial Permeability Transition Pores

Morphine Postconditioning Protects Against Reperfusion Injury: the Role of Protein Kinase C-Epsilon, Extracellular Signal-Regulated Kinase 1/2 and Mitochondrial Permeability Transition Pores

Background/Aims: The purpose of this study was to investigate the implications of protein kinase C-epsilon (PKCε), Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and mitochondrial permeability transition pore (mPTP) in myocardial protection induced by morphine postconditioning (MpostC). Methods:...

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Bibliographic Details
Main Authors: Zuolei Chen, Donat R. Spahn, Xuewei Zhang, Yingzhi Liu, Haichen Chu, Zhongkai Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Morphine
Postconditioning
Reperfusion injury
Protein kinase C epsilon
Extracellular signal-related kinases
Mitochondrial permeability transition pores
Online Access:http://www.karger.com/Article/FullText/447890

Internet

http://www.karger.com/Article/FullText/447890

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