Biomimetic single Al-OH site with high acetylcholinesterase-like activity and self-defense ability for neuroprotection

Biomimetic single Al-OH site with high acetylcholinesterase-like activity and self-defense ability for neuroprotection

Abstract Neurotoxicity of organophosphate compounds (OPs) can catastrophically cause nervous system injury by inhibiting acetylcholinesterase (AChE) expression. Although artificial systems have been developed for indirect neuroprotection, they are limited to dissociating P-O bonds for eliminating OP...

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Bibliographic Details
Main Authors: Weiqing Xu, Xiaoli Cai, Yu Wu, Yating Wen, Rina Su, Yu Zhang, Yuteng Huang, Qihui Zheng, Liuyong Hu, Xiaowen Cui, Lirong Zheng, Shipeng Zhang, Wenling Gu, Weiyu Song, Shaojun Guo, Chengzhou Zhu
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41765-x

Internet

https://doi.org/10.1038/s41467-023-41765-x

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