Identification of essential amino acid residues in the nisin dehydratase NisB

Nisin is a posttranslationally-modified antimicrobial peptide that has the ability to induce its own biosynthesis. Serines and threonines in the modifiable core peptide part of precursor nisin are dehydrated to dehydroalanines and dehydrobutyrines by the dehydratase NisB, and subsequently cysteines...

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Bibliographic Details
Main Authors: Rustem eKhusainov, Auke J. van Heel, Jacek eLubelski, Gert N.` Moll, Oscar P. Kuipers
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00102/full