Prognostic impact of HER2-low positivity in patients with HR-positive, HER2-negative, node-positive early breast cancer

Abstract Adjuvant therapy for patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-positive, early breast cancer (EBC) remains challenging. The prognostic significance of HER2-low positivity in these patients is not fully understood. In our ret...

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Bibliographic Details
Main Authors: Shohei Shikata, Takeshi Murata, Masayuki Yoshida, Hiromi Hashiguchi, Yukiko Yoshii, Ayumi Ogawa, Chikashi Watase, Sho Shiino, Hirokazu Sugino, Kenjiro Jimbo, Akiko Maeshima, Eriko Iwamoto, Shin Takayama, Akihiko Suto
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47033-8