Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1

<p>Abstract</p> <p>Background</p> <p>The mechanism by which HIV-1 induces AIDS is still unknown. Previously, synthetic peptides corresponding to the conserved immunosuppressive (isu) domain in gp41 of HIV-1 had been shown to inhibit proliferation and to modulate cytokin...

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Bibliographic Details
Main Authors: Morozov Vladimir A, Morozov Alexey V, Semaan Marwan, Denner Joachim
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Retrovirology
Subjects:
Online Access:http://www.retrovirology.com/content/9/1/67