Repeated social defeat promotes persistent inflammatory changes in splenic myeloid cells; decreased expression of β-arrestin-2 (ARRB2) and increased expression of interleukin-6 (IL-6)

Repeated social defeat promotes persistent inflammatory changes in splenic myeloid cells; decreased expression of β-arrestin-2 (ARRB2) and increased expression of interleukin-6 (IL-6)

Abstract Background Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social defeat, on behavior, hypothalamic–pituitary–adrenal (HPA)-axis and immu...

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Bibliographic Details
Main Authors: Dhaksshaginy Rajalingam, Ingeborg Nymoen, Daniel Pitz Jacobsen, Mina Baarnes Eriksen, Erik Dissen, Morten Birkeland Nielsen, Ståle Valvatne Einarsen, Johannes Gjerstad
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Neuroscience
Subjects:
Social stressors
Repeated social defeat
Bullying
ADRB2
ARRB2
IL-6
Online Access:http://link.springer.com/article/10.1186/s12868-020-00574-4

Internet

http://link.springer.com/article/10.1186/s12868-020-00574-4

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