Role of Elevated Serum TGF-β1 and the Common Promoter <i>TGFB1</i>-509C/T Polymorphism in the Development and Progression of Primary Glial Tumors and Brain Metastases

Role of Elevated Serum TGF-β1 and the Common Promoter <i>TGFB1</i>-509C/T Polymorphism in the Development and Progression of Primary Glial Tumors and Brain Metastases

<i>Background and Objectives</i>: The role of transforming growth factor-beta1 (TGF-β1) has been widely studied in the context of carcinogenesis. It has been involved in the pathogenesis of primary brain tumors or brain metastases due to its pleiotropic effects on immune regulation and t...

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Bibliographic Details
Main Authors: Elina Aleksandrova, Ivan Mindov, Bozhidar Petrov, Ivelina Dimitrova, Nikolay Petrov, Julian Ananiev, Tatyana Vlaykova, Stefan Valkanov
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Medicina
Subjects:
glial tumors
brain metastases
TGF-β1
polymorphism
immunohistochemistry
Online Access:https://www.mdpi.com/1648-9144/60/1/146

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https://www.mdpi.com/1648-9144/60/1/146

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